Research & Faculty

The MPI for Heart and Lung Research has a long and rich history in excellent research related to cardiovascular and pulmonary biology and medicine. The current institute emerged 2005 from the former MPI for Physiological and Clinical Research and expanded 2009 into a second brand-new research building.

"The mission of the MPI-HLR is to perform cutting-edge research to gain new insights into the basic molecular mechanisms that underlie cardiovascular and lung diseases. Excellent basic research (almost) inevitably gives rise to practical applications and new therapies. Hence, the MPI-HLR works closely together with the Kerckhoff Hospital in Bad Nauheim and clinical departments at the nearby universities of Frankfurt and Giessen to put scientific discoveries into practical applications. The overall scientific mission is reflected in the focus of the institute departments and independent research groups" (taken from "The Max Planck Institute for Heart and Lung Research Curiosity-Driven Basic Research to Fight Cardio-Pulmonary Diseases").


Scientific experts from all over the world work together in an rich scientific environment supported by state-of-the-art service facilities in the field of imaging, proteomics, bioinformatics, next generation sequencing and generation of transgenic animals (mouse and zebra fish).



Departments at the Max Planck Institute for Heart and Lung Research and their research focus:



Independent Research Groups of the MPI and their research focus:



Affiliated Institutes & Universities:


Vascular Research Center (VRC),  Frankfurt

Prof. Dr. Ingrid Fleming

Prof. Dr. Ralf P. Brandes



Goethe University Frankfurt

Institute of Cardiovascular Regeneration:  Prof. Dr. Stefanie Dimmeler

Department of Molecular and Cellular Neurobiology: Prof. Dr. Amparo Acker-Palmer



Justus Liebig University Gießen

Molecular Mechanisms of Emphysema, Hypoxia and Lung Aging: Prof. Dr. Norbert Weißmann

Kardiopulmonale Neurobiologie:  Prof. Dr. Wolfgang Kummer

Institute for Genetics : Prof. Dr. Reinhard Dammann

Department of Biochemistry: Prof. Dr. Lienhard Schmitz

Some example lines of research include:

•    Aging and Adaptation of the Cardiovascular System •    Alveolarization and Lung Regeneration •    Bioinformatics •    Blood Vessel growth (Angiogenesis and Arteriogenesis) •    Endothelium and Metastasis •    Genetic and Molecular Mechanisms in Organ Development •    Lung Cancer Epigenetics •    Metabolic Regulation •    Molecular Control of Heart and Skeletal Muscle Development •    Molecular Mechanisms of Lung Cancer •    Molecular Mechanisms of Pulmonary Vascular Disease •    Molecular Signalling (GPCRs, Semaphorin-Plexin-System) •    Proteomic Approaches •    Regulation of Vascular Tone/ Blood Pressure •    Stem Cells and Progenitors in Cardiovascular Research •    Stem Cells and the Regeneration of Contractile Tissue and the Lung •    Structure and Development of the Alveolus

© 2017 Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany